Friday, 16 April 2010

Saturday, 17 April 2010

08.30

Symposium 1
Predictors, moderators and mediators of symptom improvement in major depressive disorder
Session Chair: G. Papakostas, Massachusetts General Hospital, USA

Clinical factors serving as predictors, moderators, and mediators of symptom improvement
P. Joyce, University of Otago, New Zealand

The role of electroencephalography in predicting and/or correlating with treatment outcome in major depressive disorder
C. Mulert, University of Munich, Germany

Genetics of antidepressant response
A. Serretti, University of Bologna, Italy

Predictors, moderators, and mediators of symptom improvement in major depressive disorder: overview, definition, and significance
G. Papakostas, Massachusetts General Hospital, USA

Symposium 2
CANMAT: Managing depression in bipolar and unipolar patients: Evidence based approaches from CANMAT guidelines
Session Chair: S. Kennedy, University Health Network, University of Toronto, Canada

Evolution of evidence to support distinct management approaches
S. Kennedy, University Health Network, Canada

A sequenced pharmacotherapy for MDD in 2010
R. Lam, The University of British Columbia, Canada

A sequenced pharmacotherapy for bipolar depression in 2010: contrasts and similarities
L. Yatham, The University of British Columbia, Canada

Disorder specific psychotherapy: Contrasts between major depressive disorder and bipolar depression
S. Parikh, University of Toronto, Canada

Symposium 3
Cognitive and temperamental vulnerability to depression
Session Chair: C. Kuehner, Central Institute of Mental Health, Germany
Co-Chair: J. Ormel, University Medical Center, Netherlands

Internalizing problems during adolescence: the role of temperament-environment interactions in the TRAILS study
J. Ormel, University Medical Center, Netherlands

Cognitive vulnerability-stress models of depression in the transition from early to middle adolescence
B Hankin, The University of Denver, USA

The role of rumination as a cognitive vulnerability trait for depression
C.Kuehner, Central Institute of Mental Health, Germany

Emotion dysregulation and stress reactivity in children at risk for depression
I. H. Gotlib, Stanford University, USA

Depression in Families – What we have learned and how we can help
M. Weissman, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, USA

Symposium 4
The International Society for Bipolar Disorders – Bipolar disorder: new directions in assessment and management
Session Chair: L. Yatham, The University of British Columbia, Canada

Consensus guidelines for the safety monitoring of bipolar disorder treatments
M. Berk¹,²,³, ¹University of Melbourne, Australia; ²Barwon Health and The Geelong Clinic, Australia, ³Orygen Research Centre, Australia; ⁴Mental Health Research Institute of Victoria, Australia

The International Society of Bipolar Disorders (ISBD) task force on the nomenclature of course and outcome in bipolar disorders
Speaker to be confirmed

Women's health issues in bipolar disorder
A. Ozerdem, Dokuz Eylul University, Turkey

Bipolar disorder: Re-cognition
Ivan Torres, Canada

Symposium 5
Diet and nutrition: A new perspective in psychiatry
Session Chair: F. Gomez-Pinilla, University of California, USA

Diet and exercise therapy and mechanisms for neurological disorders
F. Gomez-Pinilla, University of California, USA

The role of omega-3 fatty acids in the prevention and treatment of the common mental disorders
L. Williams, University of Melbourne, Australia

The role of nutritional deficiency states in depression
R. Stewart, Kings College London, UK
Diet as a modifiable risk factor for the common mental disorders: Evidence and mechanisms
F. Jacka, University of Melbourne, Australia

Symposium 6
Depression in primary care
Session Chair: A. Tylee, Kings College London, UK

Quality indicators for the management of depression in the UK general practice contract: Quantitative and qualitative evaluation
T. Kendrick, University of Southampton, United Kingdom

Programme to increase equity of access to high quality mental health services in primary care (AMP)
C. Dowrick, University of Liverpool, UK

Depression and somatic symptoms experience from the DIAMOND study: a longitudinal naturalistic study of depression in primary care in Victoria, Australia
J. Gunn, The University of Melbourne, Australia

UPBEAT-UK, a cohort and qualitative studies of patients with coronary heart disease and depression in primary care
A. Tylee, Kings College London, UK

Sunday, 18 April 2010

Neurostimulation for depression: An overview
P. Giacobbe, University Health Network, Canada

Symposium 7
Meeting the challenge of resistant depression
Session Chair: B. Lerer, Hebrew University Medical Center, Israel

New therapeutic targets to address efficacy limitations in the treatment of depression
S. Stahl, University of California, USA

Endocrine approaches to augmenting antidepressants
B. Lerer, Hebrew University Medical Center, Israel

Recent advances in ECT and other brain stimulation techniques for treatment resistant depression
M. George, Medical University of South Carolina, USA

Psychotherapeutic strategies in the treatment of chronic / therapy resistant depression
M. Berger, University of Freiberg, Germany

Symposium 8
New trends in bipolar disorders research
Session Chair: M. Preisig, University Hospital Center and University of Lausanne, Switzerland

The mood spectrum: A new perspective
J.Angst, University Hospital Zurich, Switzerland

Genetics of bipolar disorder
N. Craddock, Cardiff University, UK

Mental disorders and cardio-vascular risk factors: Results of a population-based survey
M. Preisig, University of Lausanne, Switzerland

Latest developments in the treatment of bipolar disorder
I. Goikolea, University of Barcelona, Spain

Symposium 9
Psychosocial interventions in bipolar disorder: theory, evidence base, prevention and management of comorbidity
Session Chair: R. Morriss, University of Nottingham, UK

Efficacy, nature and role of psychological interventions in the overall management of bipolar disorder
R.K. Morriss, University of Nottingham, UK

Psychological processes leading to manic and depressive episodes
S.L. Johnson, University of California Berkeley, USA

Theory and management of anxiety and substance use disorder in people with bipolar disorder
S. Jones, Spectrum Centre for Mental Health Research, University of Lancaster, UK

Psychological processes leading to the development of bipolar disorder in people at high risk
R.P. Bentall, University of Bangor, UK

New developments in the rational site-directed pharmacotherapy of depression
P.Blier, University of Ottawa Institute of Mental Health Research, Canada

Social predictors of depression symptom severity in a sample of African American mothers
C. Ronzio*¹,², S.J. Mitchell², ¹Children''s National Medical Center, USA, ²George Washington University Medical Center, USA

Birth weight, stressful events and depression: Testing the fetal programming hypothesis
I. Colman*¹, D. Gaysina², P.B. Jones³, M. Richards², ¹University of Alberta, ²MRC Unit for Lifelong Health and Ageing, UK, ³University of Cambridge, UK

Interaction between serotonin transporter promoter polymorphism (5-HTTLPR), age-related stressful life events and trait neuroticism on depressive symptomatology in non-clinical volunteers
E. Verschoor*, C.R. Markus, Maastricht University, Netherlands

14:45

Reformulating the problem in psychotherapy for depression
M. Crowe*, L. Whitehead, D. Carlyle, J. Carter, University of Otago, Christchurch, New Zealand

Relapse prevention in recurrent depression
M. Hautzinger*, Eberhard Karls University Tuebingen, Germany,

Genome-wide association-, replication- and neuroimaging study implicates HOMER1 in the aetiology of major depression
M.D.C. Rietschel*¹, M. Mattheisen², J. Frank¹, J. Treutlein¹, A. Meyer-Lindenberg¹, S. Cichon²
¹University of Heidelberg, Germany, ²University of Bonn, Germany

15:00

Hot and cold neuropsychological impairment in severe depression
K.M. Douglas*¹, L. Johnston², P. Maruff³, R. Knight⁴, R.J. Porter¹, ¹University of Otago, New Zealand, ²University of Canterbury, New Zealand, ³CogState Limited, Australia, ⁴University of Otago, Dunedin, New Zealand

The effectiveness of evidence-based treatments for major depressive disorder in a routine clinical setting, results from an observational study
F. Peeters*, M. Huibers, J. Roelofs, Maastricht University, Netherlands,

A novel hypothesis postulating the etiopathobiologies in obsessive-compulsive symptoms using a family genogram of obsessional cleaners and three known genetic disorders
E.M. Peter-Ross*, University of Cape Town, South Africa

15:15

Comorbid depression and binge drinking: Risk for suicidality among youth
S. Archie*¹,³, A. Zangeneh Kazemi², N. Akhtar-Danesh¹, ¹McMaster University, Canada, ²University of Waterloo, Canada, ³St. Joseph's Healthcare Hamilton, Canada

Which anxiety symptoms predict long-term morbidity in major depression
W. Coryell*, University of Iowa, Carver College of Medicine, USA

Regulatory T cells increased while IL-1beta decreased during antidepressant therapy
H. Himmerich*¹,², L. Rink², ¹RWTH Aachen University, Germany, ²University of Leipzig, Germany,

15:30

Integration of psychological and neuroendocrine parameters by experience or stress-related disorder
K. Hegadoren*¹, K. Chivers-Wilson², C. Norris¹, R.A. Lanius³, N.J. Coupland¹
¹University of Alberta, Canada, ²University of Calgary, Canada, ³University of Western Ontario, Canada

The quality of life in bipolar disorder (QoL.BD) scale: development and psychometric properties
G. Murray*¹, E.E. Michalak², ¹Swinburne University of Technology, Australia, ²University of British Columbia, Canada

The impact of depressive disorders and treatment with an antidepressant on the activity of P-glycoprotein at the blood-brain barrier. Results of 2 PET Studies
O.L. de Klerk*¹, A.T.M Willemsen¹, F.J. Bosker¹, P. Meerlo², R.A Dierckx¹, J.A den Boer¹
¹University Medical Center Groningen, Germany, ²Univeristy of Groningen, Germany

15:45

Depression-related absenteeism and presenteeism amongst employed Australian adults: Do working conditions influence the health and economic consequences?
F.M. Cocker*¹, A. Martin², J. Scott², K. Sanderson¹, Menzies Research Institute, Australia, University of Tasmania, Australia

Longer-term outcome in treatment-resistant depression: Prediction of remission, recovery and episode persistence
A.J. Cleare*¹,³, A. Fekadu¹,², L.J. Rane¹,², S.C Wooderson¹,², K. Markopoulou¹,², L. Poon²
¹King's College London, UK, ²South London and Maudsley NHS Foundation Trust, UK, ³The NIHR Biomedical Research Centre at South London and Maudsley NHS Trust & Institute of Psychiatry (King’s College London), UK

The influence of HF-rTMS treatment on 5-HT 2A receptors in medication-resistant unipolar depression
C. Baeken*¹, R. De Raedt², M.A. Vanderhasselt², A. Bossuyt¹, ¹UZBrussel, Belgium, ²Ugent, Belgium

16:00

Risk factors for and negative behavioral/social outcomes associated with dysthymia (DYS), alone or co-morbid with major depression (DD): Findings from NESARC Waves 1 and 2
J.M. Mossey*, G. Knoeller, Drexel University School of Public Health, USA

A prospective study of psychiatric comorbidity of DSM-IV bipolar I and II disorders
E. T Isometsä*¹,², O. Mantere¹,², M. Ketokivi³, O. Kiviruusu¹, K. Suominen¹,², H.M. Valtonen¹,²
¹National Institute of Health and Welfare, Finland, ²Helsinki University Central Hospital, Finland, ³Helsinki University of Technology,Finland

Elevated cortisol levels, interpersonal stress, and the development of an affective disorder among the offspring of parents with bipolar disorder
M. Ellenbogen*¹, C. Ostiguy¹, A.M. Linnen¹, S. Hodgins², Concordia University, Canada, ²King's College London, UK

16:15

Psychosocial impairment in dysthymic disorder in the NESARC Study
D. Hellerstein*¹,², V. Agosti¹, M. Bosi³, S. Black⁴, ¹New York State Psychiatric Institute, USA, ²Columbia University, USA, ³Luigi Sacco Hospital, Università degli Studi, Italy, ⁴Stonybrook University, USA

Depression incidence rates and predictors of major and minor depression in patients with chronic heart failure
N. Lossnitzer*¹, W. Herzog¹, G. Gelbrich², S.Störk³, B. Wild¹, ¹University of Heidelberg, Germany, ²University of Leipzig, Germany, ³University of Würzburg, Germany,

Increased pituitary-adrenal activation and shortened gestation in depressed pregnant women
V. O’Keane*¹, S. Lightman³, M. Marsh⁵, S. Pawlby², A. Papadoupolos², K. Patrick¹, ¹Trinity College Dublin, Ireland,²Institute of Psychiatry, UK, ³University of Bristol, UK, ⁴King's College London, UK, ⁵King's College Hospital, UK

All attendees to meet in reception at 18:30, Buses depart for Gala Dinner from front of hotel at 18:45

Gala Dinner to take place at the Vancouver Aquarium, Stanley Park

Monday, 19 April 2010

Symposium 10
Screening for bipolar disorder: how useful are currently available instruments and what do they tell us about the nosology and epidemiology of mood disorders?
Session Chair: A. Young, University of British Columbia, Canada

Testing the Hypomania Checklist-32 (HCL-32) and Mood Disorder Questionnaire (MDQ): Going beyond samples of patients with affective disorders
T.D. Meyer, Newcastle University, UK

Transcultural stability and variation of hypomania assessed by the HCL-32
J. Angst, Psychiatrische Universitätsklinik, Switzerland

What do bipolar screening questionnaires tell us about the nosology of depression?
D.J Smith, Cardiff University, UK

Characteristics of patients with bipolar disorder presenting a current major depressive episode: Analysis in eight countries
A. Young, University of British Columbia, Canada

Symposium 11
Oxidative biology in psychiatric disorders: novel mechanism of disease and novel therapeutic opportunities
Session Chair: T. Young, University of British Columbia, Canada

Psychopharmacological analysis of mice with neuron specific accumulation of mitochondrial DNA mutations
T. Kato, RIKEN Brain Science Institute, Japan

Evidence of mitochondrial dysfunction and oxidative damage in Bipolar Disorder: findings from postmortem brain and peripheral cells
A.C. Andreazza, University of British Columbia, Canada, Hospital de Clinicas de Porto Alegre, Brazil

Systemic toxicity in mood episodes
F. Kapczinski, Hospital de Clinicas de Porto Alegre, Brazil

Oxidative biology in psychiatric disorders: Novel mechanism of disease and novel therapeutic opportunities
M. Berk, University of Melbourne, Australia, Mental Health Research Institute, Australia

Symposium 12
Creating HOPE: Health through online and offline peer support and education
Session Chair: S. Tse, University of Hong Kong, Hong Kong

Overview: Creating HOPE project and balance NZ
C. Doughty, University of Otago, New Zealand

The wellness recovery action plan (WRAP): Is it well enough to use?
L. McIntyre, Balance NZ Bipolar and Depression
Network, New Zealand

Internet-based WRAP (I-WRAP)
F. Bristol, Balance NZ Bipolar and Depression Network, New Zealand

WRAP, is it empowering for all?
L. Wilson, University of Otago, New Zealand

Economics: Friend or foe?
M. Knapp, London School of Economics, UK